Gefitinib-loaded DSPE-PEG2000 nanomicelles with CD133 aptamers target lung cancer stem cells
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منابع مشابه
Gefitinib-loaded DSPE-PEG2000 nanomicelles with CD133 aptamers target lung cancer stem cells
BACKGROUND Lung cancer stem cells (CSCs) are considered to be the seed of lung cancer, and CD133 is a marker of lung CSCs. Here, we developed gefitinib-loaded poly(ethylene glycol) 2000-distearoylphosphatidylethanolamine nanomicelles with CD133 aptamers (M-Gef-CD133) to eliminate CD133+ lung CSCs. METHODS M-Gef-CD133 was prepared using a lipid-film-based approach. The targeting and activity o...
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ژورنال
عنوان ژورنال: World Journal of Surgical Oncology
سال: 2017
ISSN: 1477-7819
DOI: 10.1186/s12957-017-1230-4